Critical Reviews
BORC, A Multisubunit Complex that Regulates Lysosomal Positioning
Bloc-1-related complex(BORC) was discovered by Pu et al. when researching the protein interactions of biogenesis of lysosome related organelles complex-1(BLOC-1), a study that was being conducted in the wake of previous studies of Arl8, a lysosome associated protein, and its relationship to diseases such as Hermanksy-Pudlak syndrome, one of many diseases that affects lysosome related organelles(LROs), such as melanosomes.